Zidovudine CAS NO.30516-87-1

Chemical Name: 1-(3-azido-2,3-dideoxy--D-ribofuranosyl)-5-methylpyrimidin 2,4(1H,3H)-dione Molecular Formula: C10H13N5O4 Molecular Weight: 267.24 …

Chemical Name: 1-(3-azido-2,3-dideoxy--D-ribofuranosyl)-5-methylpyrimidin 2,4(1H,3H)-dione Molecular Formula: C10H13N5O4 Molecular Weight: 267.24 Mechanism of Action: ZidovudineAZTis an antiviral drug, which has high activity to reverse transcript virus and HIV in vitro. Within cells infected by the virus, Zidovudine is converted to the Zidovudine triphosphate by the cellular thymidine kinase, which can selectively inhibit HIV reverse transcriptase. In this way HIV chain synthesis can be terminated. Indication and Usage: Zidovudine is an antiviral drug, belonging to reverse transcriptase inhibitors. The first anti-HIV drug approved by FDA of the United States. The major component is the cock-tail treatment regimen. Be used alone as prophylactic drug and also as maternal-fetal HIV transmission prevention drug.